1. Pharmacological effects

 For ofloxacin of its antibacterial activity ofloxacin about two times that of its main mechanism for the inhibition of bacterial DNA gyrase activity, inhibit bacterial DNA replication. a broad spectrum antibacterial and antifungal powerful features, the majority of enterobacteriaceae bacteria such as klebsiella pneumoniae bacteria white, proteus is, typhoid salmonella spp, shigella species, influenza bacteria, some of escherichia coli, pseudomonas aeruginosa, gonorrhea, which are strong antibacterial activity; some staph , Streptococcus pneumoniae, Chlamydia also a good antibacterial effect.

2.Indications

Apply to gram-negative bacteria and gram-positive bacteria in the sensitive strains caused by the severe respiratory, urinary system, digestive system and skin and soft tissue infections, sepsis, typhoid paratyphoid Shigellosis and by neisseria gonorrhoeae, Chlamydia trachomatis caused by urethritis, cervicitis.

3.Usage and consumption

Intravenous drip. Adult a 0.1 ~ 0.2 g, on the 1st 2nd, or compliance.

4.Adverse reaction

Occasionally anorexia, nausea, vomiting, diarrhea, insomnia, dizziness, headache, rash and elevated serum ALT and stimulate the local injection of symptoms, both general tolerance, treatment After could disappear.

5.Of taboos

Right quinolones allergies, pregnancy, breast-feeding women, under the age of 16 patients and is contraindicated in patients with epilepsy.

6.Note

A renal dysfunction or anti should reduction.
two anti nervous system disease patients.
at the same time to avoid the use of theophylline. For application at the same time, should monitor the serum concentration of theophylline to adjust their dose.
with warfarin or its derivatives application at the same time, prothrombin time should be monitored or other coagulation tests.
five patients with sexually transmitted diseases, syphilis serology should conduct inspections to avoid delays on the treatment of syphilis.
infusion rate to 6 per 100 ml at least 60 minutes, can cause excessive intravenous drip to stimulate the central nervous system symptoms or reactions.

7.Storage

Shading, closed, the preservation of the shade home.